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CAZyme Information: MGYG000003359_04588

You are here: Home > Sequence: MGYG000003359_04588

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Paenibacillus_A sp900766135
Lineage Bacteria; Firmicutes; Bacilli; Paenibacillales; Paenibacillaceae; Paenibacillus_A; Paenibacillus_A sp900766135
CAZyme ID MGYG000003359_04588
CAZy Family GH5
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
579 65031.78 6.3322
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003359 5721146 MAG United States North America
Gene Location Start: 18696;  End: 20435  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000003359_04588.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH5 73 353 8e-89 0.9927536231884058
CBM46 382 468 1.8e-26 0.9885057471264368

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam18448 CBM46 2.24e-57 472 575 1 105
Carbohydrate binding domain. Carbohydrate active enzymes (CAZYmes) that target recalcitrant polysaccharides are modular enzymes containing noncatalytic carbohydrate-binding modules (CBMs) that direct enzymes to their cognate substrate, thus potentiating catalysis. The structure of Bacillus halodurans endo-beta-1,4-glucanase B (Cel5B) reveals that CBM46 is tightly associated with the catalytic module and, dependent on the glucan presented to the enzyme, can contribute directly to substrate binding or play a targeting role in directing the enzyme to regions of the plant cell wall rich in the polysaccharide hydrolyzed by the enzyme. The CBM46 domain displays a classic beta-sandwich jelly roll fold. Against beta-1,3-1,4-glucans CBM46 domain participates in productive substrate binding and thus plays a direct role in the hydrolytic activity of the enzyme.
pfam00150 Cellulase 2.15e-54 66 354 1 271
Cellulase (glycosyl hydrolase family 5).
COG2730 BglC 6.73e-47 46 363 41 371
Aryl-phospho-beta-D-glucosidase BglC, GH1 family [Carbohydrate transport and metabolism].
pfam03442 CBM_X2 1.08e-11 387 468 7 83
Carbohydrate binding domain X2. This domain binds to cellulose and to bacterial cell walls. It is found in glycosyl hydrolases and in scaffolding proteins of cellulosomes (multiprotein glycosyl hydrolase complexes). In the cellulosome it may aid cellulose degradation by anchoring the cellulosome to the bacterial cell wall and by binding it to its substrate. This domain has an Ig-like fold.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QSF44195.1 2.96e-273 30 574 23 568
AIQ33839.1 4.52e-273 38 576 34 572
AIQ72470.1 9.11e-273 38 576 34 572
AWV31838.1 1.05e-271 38 576 34 572
ASA25821.1 2.12e-271 45 576 41 572

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5E0C_A 1.86e-233 49 575 10 536
StructuralInsight of a Trimodular Halophilic Cellulase with a Family 46 Carbohydrate-Binding Module [Bacillus sp. BG-CS10]
5XRC_A 3.59e-233 49 577 43 571
ATrimodular GH5_4 Subfamily Endoglucanase Structure with Large Unit Cell [Bacillus sp. BG-CS10],5XRC_B A Trimodular GH5_4 Subfamily Endoglucanase Structure with Large Unit Cell [Bacillus sp. BG-CS10],5XRC_C A Trimodular GH5_4 Subfamily Endoglucanase Structure with Large Unit Cell [Bacillus sp. BG-CS10]
4V2X_A 2.55e-231 49 574 58 583
ChainA, Endo-beta-1,4-glucanase (cellulase B) [Halalkalibacterium halodurans]
5E09_A 5.08e-226 49 575 10 536
StructuralInsight of a Trimodular Halophilic Cellulase with a Family 46 Carbohydrate-Binding Module [Bacillus sp. BG-CS10]
4YZP_A 2.24e-82 41 556 10 522
Crystalstructure of a tri-modular GH5 (subfamily 4) endo-beta-1, 4-glucanase from Bacillus licheniformis [Bacillus licheniformis],4YZT_A Crystal structure of a tri-modular GH5 (subfamily 4) endo-beta-1, 4-glucanase from Bacillus licheniformis complexed with cellotetraose [Bacillus licheniformis]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P23550 3.85e-259 35 574 21 563
Endoglucanase B OS=Paenibacillus lautus OX=1401 GN=celB PE=3 SV=1
P28621 9.12e-57 50 352 43 341
Endoglucanase B OS=Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B) OX=573061 GN=engB PE=3 SV=1
P10477 3.14e-55 52 371 60 365
Cellulase/esterase CelE OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=celE PE=1 SV=2
P28623 6.61e-55 50 352 44 339
Endoglucanase D OS=Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B) OX=573061 GN=engD PE=1 SV=2
P23660 8.05e-49 48 354 26 333
Endoglucanase A OS=Ruminococcus albus OX=1264 GN=celA PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000329 0.998914 0.000182 0.000251 0.000172 0.000146

TMHMM  Annotations      download full data without filtering help

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