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CAZyme Information: MGYG000003375_00541

You are here: Home > Sequence: MGYG000003375_00541

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Corynebacterium striatum
Lineage Bacteria; Actinobacteriota; Actinomycetia; Mycobacteriales; Mycobacteriaceae; Corynebacterium; Corynebacterium striatum
CAZyme ID MGYG000003375_00541
CAZy Family GT53
CAZyme Description putative arabinosyltransferase C
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1121 122236.24 4.8797
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003375 2788808 MAG United States North America
Gene Location Start: 112246;  End: 115611  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.2.-

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT53 20 1112 0 0.9971401334604385

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam04602 Arabinose_trans 0.0 206 650 1 445
Mycobacterial cell wall arabinan synthesis protein. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol.
pfam14896 Arabino_trans_C 2.34e-178 713 1112 1 384
EmbC C-terminal domain. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol. This domain represents the C-terminal extracellular domain that is likely to bind to carbohydrate.
pfam17689 Arabino_trans_N 1.21e-50 46 202 1 155
Arabinosyltransferase concanavalin like domain. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QQE52411.1 0.0 1 1121 1 1121
ATZ09923.1 0.0 8 1121 1 1114
ATZ07310.1 0.0 8 1121 1 1114
ART20129.1 0.0 1 1121 1 1121
AMO88994.1 0.0 1 1121 1 1121

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
7BVE_A 1.08e-259 20 1113 13 1073
Cryo-EMstructure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155],7BVE_B Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155]
7BVH_A 2.67e-259 20 1113 26 1086
Crystalstructure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose [Mycolicibacterium smegmatis MC2 155],7BVH_B Crystal structure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose [Mycolicibacterium smegmatis MC2 155]
7BWR_A 4.26e-236 20 1115 24 1082
Mycobacteriumsmegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound asymmetric 'active state' [Mycolicibacterium smegmatis MC2 155],7BWR_B Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound asymmetric 'active state' [Mycolicibacterium smegmatis MC2 155],7BX8_A Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in symmetric 'resting state' [Mycolicibacterium smegmatis MC2 155],7BX8_B Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in symmetric 'resting state' [Mycolicibacterium smegmatis MC2 155]
6X0O_A 6.89e-236 20 1115 24 1082
Single-ParticleCryo-EM Structure of Arabinosyltransferase EmbB from Mycobacterium smegmatis [Mycolicibacterium smegmatis MC2 155]
7BVC_B 7.31e-236 20 1115 24 1082
Cryo-EMstructure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155],7BVG_B Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with di-arabinose. [Mycolicibacterium smegmatis MC2 155]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q50393 3.04e-256 20 1113 13 1073
Probable arabinosyltransferase C OS=Mycolicibacterium smegmatis OX=1772 GN=embC PE=3 SV=2
Q7TVN4 4.55e-242 20 1106 27 1086
Probable arabinosyltransferase C OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) OX=233413 GN=embC PE=3 SV=1
Q9CDA7 2.44e-241 23 1106 12 1063
Probable arabinosyltransferase C OS=Mycobacterium leprae (strain TN) OX=272631 GN=embC PE=3 SV=1
P9WNL5 2.54e-241 20 1106 27 1086
Probable arabinosyltransferase C OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=embC PE=1 SV=1
P9WNL4 3.58e-241 20 1106 27 1086
Probable arabinosyltransferase C OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=embC PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000003 0.000008 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

start end
21 43
213 230
250 267
323 345
357 374
412 434
447 469
516 533
546 563
567 589
602 624
646 668
689 711