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CAZyme Information: MGYG000003396_00128
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Clostridium sp900766315 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Clostridiales; Clostridiaceae; Clostridium; Clostridium sp900766315 | |||||||||||
| CAZyme ID | MGYG000003396_00128 | |||||||||||
| CAZy Family | GH23 | |||||||||||
| CAZyme Description | Soluble lytic murein transglycosylase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 9168; End: 9710 Strand: - | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd16896 | LT_Slt70-like | 1.38e-78 | 30 | 174 | 1 | 146 | uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
| cd13401 | Slt70-like | 1.82e-53 | 28 | 178 | 1 | 152 | 70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda. |
| cd00254 | LT-like | 2.19e-42 | 48 | 173 | 1 | 111 | lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
| COG0741 | MltE | 4.29e-36 | 1 | 179 | 109 | 287 | Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell wall/membrane/envelope biogenesis]. |
| cd16893 | LT_MltC_MltE | 2.19e-31 | 35 | 173 | 1 | 162 | membrane-bound lytic murein transglycosylases MltC and MltE, and similar proteins. MltC and MltE are periplasmic, outer membrane attached lytic transglycosylases (LTs), which cleave beta-1,4-glycosidic bonds joining N-acetylmuramic acid and N-acetylglucosamine in the cell wall peptidoglycan, yielding 1,6-anhydromuropeptides. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AYE35401.1 | 4.13e-81 | 1 | 180 | 1 | 180 |
| QAS60789.1 | 4.13e-81 | 1 | 180 | 1 | 180 |
| ASW42505.1 | 3.93e-79 | 1 | 180 | 1 | 180 |
| SLK19900.1 | 1.07e-76 | 1 | 179 | 1 | 179 |
| ATD56881.1 | 1.07e-76 | 1 | 179 | 1 | 179 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5MPQ_A | 5.15e-19 | 21 | 179 | 407 | 559 | BulgecinA: The key to a broad-spectrum inhibitor that targets lytic transglycosylases [Neisseria meningitidis] |
| 5O1J_A | 5.17e-19 | 21 | 179 | 411 | 563 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
| 6FPN_B | 5.18e-19 | 21 | 179 | 417 | 569 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
| 5O24_A | 5.19e-19 | 21 | 179 | 421 | 573 | Lytictransglycosylase in action [Neisseria meningitidis] |
| 5O29_A | 5.21e-19 | 21 | 179 | 427 | 579 | Lytictransglycosylase in action [Neisseria meningitidis] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| O31608 | 4.63e-21 | 31 | 172 | 58 | 179 | Putative murein lytic transglycosylase YjbJ OS=Bacillus subtilis (strain 168) OX=224308 GN=yjbJ PE=3 SV=1 |
| O64046 | 1.32e-20 | 29 | 173 | 1418 | 1542 | Probable tape measure protein OS=Bacillus phage SPbeta OX=66797 GN=yomI PE=3 SV=1 |
| O31976 | 1.32e-20 | 29 | 173 | 1418 | 1542 | SPbeta prophage-derived uncharacterized transglycosylase YomI OS=Bacillus subtilis (strain 168) OX=224308 GN=yomI PE=3 SV=2 |
| P27380 | 9.28e-14 | 32 | 140 | 6 | 104 | Transglycosylase OS=Enterobacteria phage PRD1 OX=10658 GN=VII PE=1 SV=3 |
| C5BCE9 | 1.33e-13 | 31 | 176 | 189 | 356 | Membrane-bound lytic murein transglycosylase C OS=Edwardsiella ictaluri (strain 93-146) OX=634503 GN=mltC PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.835262 | 0.132243 | 0.030936 | 0.000344 | 0.000186 | 0.001023 |
