DNA-binding transcriptional regulator, LacI/PurR family [Transcription].

ligand binding domain of the LacI transcriptional regulator family belonging to the type 1 periplasmic-binding fold protein superfamily. Ligand binding domain of the LacI transcriptional regulator family belonging to the type 1 periplasmic-binding fold protein superfamily. In most cases, ligands are monosaccharide including lactose, ribose, fructose, xylose, arabinose, galactose/glucose, and other sugars. The LacI family of proteins consists of transcriptional regulators related to the lac repressor. In this case, the domain sugar binding changes the DNA binding activity of the repressor domain.

Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.

GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants [Signal transduction mechanisms].

ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus Metalliredigens (strain Qymf) and its close homologs. This group includes the ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus metalliredigens (strain Qymf) and its close homologs. Qymf is a strict anaerobe that could be grown in the presence of borax and its cells are straight rods that produce endospores. This group is a member of the LacI-GalR family repressors that are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.

ChainA, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'],6ZXM_B Chain B, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'],6ZXM_C Chain C, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'],6ZXM_D Chain D, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'],6ZXM_E Chain E, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'],6ZXM_F Chain F, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)']

ChainA, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'],6ZXB_B Chain B, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)']

ChainA, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'],6ZXC_B Chain B, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'],6ZXC_C Chain C, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'],6ZXC_D Chain D, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)']

SadC(300-487) from Pseudomonas aeruginosa PAO1 [Pseudomonas aeruginosa PAO1],4WXO_B SadC (300-487) from Pseudomonas aeruginosa PAO1 [Pseudomonas aeruginosa PAO1],4WXO_C SadC (300-487) from Pseudomonas aeruginosa PAO1 [Pseudomonas aeruginosa PAO1]

SadC(323-487) from Pseudomonas aeruginosa PAO1 [Pseudomonas aeruginosa PAO1]

Probable diguanylate cyclase DgcC OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) OX=199310 GN=dgcC PE=3 SV=1

Probable diguanylate cyclase DgcC OS=Escherichia coli (strain K12) OX=83333 GN=dgcC PE=1 SV=1

Uncharacterized signaling protein PA3311 OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=PA3311 PE=3 SV=1

Uncharacterized protein YhcK OS=Bacillus subtilis (strain 168) OX=224308 GN=yhcK PE=4 SV=1

Catabolite control protein A OS=Bacillus subtilis (strain 168) OX=224308 GN=ccpA PE=1 SV=1