Species | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Lineage | Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; | |||||||||||
CAZyme ID | MGYG000003797_01406 | |||||||||||
CAZy Family | CBM40 | |||||||||||
CAZyme Description | Sialidase B | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 239; End: 2563 Strand: - |
Family | Start | End | Evalue | family coverage |
---|---|---|---|---|
GH33 | 314 | 752 | 5.8e-75 | 0.9327485380116959 |
CBM40 | 123 | 302 | 9e-60 | 0.9608938547486033 |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
COG4409 | NanH | 0.0 | 1 | 773 | 1 | 728 | Neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis]. |
cd15482 | Sialidase_non-viral | 5.85e-56 | 314 | 760 | 5 | 338 | Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases. |
pfam02973 | Sialidase | 1.82e-27 | 122 | 302 | 8 | 185 | Sialidase, N-terminal domain. |
pfam13088 | BNR_2 | 3.60e-26 | 537 | 737 | 82 | 275 | BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases. |
COG4692 | COG4692 | 1.84e-04 | 575 | 736 | 195 | 352 | Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis]. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
VFH50122.1 | 0.0 | 1 | 774 | 1 | 740 |
CAR69021.1 | 0.0 | 1 | 774 | 1 | 740 |
AVD75144.1 | 0.0 | 1 | 774 | 1 | 740 |
CBW36430.1 | 0.0 | 1 | 774 | 1 | 740 |
VFH36906.1 | 0.0 | 1 | 774 | 1 | 740 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
4YW1_A | 0.0 | 117 | 774 | 1 | 658 | ChainA, Neuraminidase C [Streptococcus pneumoniae TIGR4],4YW1_B Chain B, Neuraminidase C [Streptococcus pneumoniae TIGR4],4YW2_A Chain A, Neuraminidase C [Streptococcus pneumoniae TIGR4],4YW2_B Chain B, Neuraminidase C [Streptococcus pneumoniae TIGR4],4YW3_A Chain A, Neuraminidase C [Streptococcus pneumoniae TIGR4],4YW3_B Chain B, Neuraminidase C [Streptococcus pneumoniae TIGR4],4YW4_A Streptococcus pneumoniae sialidase NanC [Streptococcus pneumoniae],4YW4_B Streptococcus pneumoniae sialidase NanC [Streptococcus pneumoniae],4YW5_A Chain A, Neuraminidase C [Streptococcus pneumoniae TIGR4],4YW5_B Chain B, Neuraminidase C [Streptococcus pneumoniae TIGR4],5F9T_A Chain A, Neuraminidase C [Streptococcus pneumoniae TIGR4],5F9T_B Chain B, Neuraminidase C [Streptococcus pneumoniae TIGR4] |
4YZ1_A | 0.0 | 118 | 774 | 21 | 677 | CrystalStructure of Streptococcus pneumoniae NanC, apo structure. [Streptococcus pneumoniae TIGR4],4YZ1_B Crystal Structure of Streptococcus pneumoniae NanC, apo structure. [Streptococcus pneumoniae TIGR4],4YZ2_A Crystal Structure of Streptococcus pneumoniae NanC, in complex with 2-deoxy-2,3-didehydro-N-acetylneuraminic acid. [Streptococcus pneumoniae],4YZ2_B Crystal Structure of Streptococcus pneumoniae NanC, in complex with 2-deoxy-2,3-didehydro-N-acetylneuraminic acid. [Streptococcus pneumoniae],4YZ3_A Crystal Structure of Streptococcus pneumoniae NanC, in complex with Oseltamivir. [Streptococcus pneumoniae TIGR4],4YZ3_B Crystal Structure of Streptococcus pneumoniae NanC, in complex with Oseltamivir. [Streptococcus pneumoniae TIGR4],4YZ4_A Crystal Structure of Streptococcus pneumoniae NanC, in complex with N-Acetylneuraminic acid. [Streptococcus pneumoniae],4YZ4_B Crystal Structure of Streptococcus pneumoniae NanC, in complex with N-Acetylneuraminic acid. [Streptococcus pneumoniae],4YZ5_A Crystal Structure of Streptococcus pneumoniae NanC, in complex with 3-Sialyllactose [Streptococcus pneumoniae],4YZ5_B Crystal Structure of Streptococcus pneumoniae NanC, in complex with 3-Sialyllactose [Streptococcus pneumoniae] |
2JKB_A | 1.32e-225 | 118 | 773 | 29 | 686 | Crystalstructure of Streptococcus pneumoniae NanB in complex with 2, 7-anhydro-Neu5Ac [Streptococcus pneumoniae TIGR4] |
2VW0_A | 1.91e-225 | 118 | 773 | 40 | 697 | Crystalstructure of the NanB sialidase from Streptococcus pneumoniae [Streptococcus pneumoniae],2VW1_A Crystal structure of the NanB sialidase from Streptococcus pneumoniae [Streptococcus pneumoniae],2VW2_A Crystal structure of the NanB sialidase from Streptococcus pneumoniae [Streptococcus pneumoniae],4FOQ_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-aminoethanesulfonic acid [Streptococcus pneumoniae],4FOV_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 3-Cyclohexyl-1-propylsulfonic acid [Streptococcus pneumoniae],4FOW_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 3-ammoniopropane-1-sulfonate [Streptococcus pneumoniae],4FOY_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-(Benzylammonio)ethanesulfonate [Streptococcus pneumoniae],4FP2_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2[(Cyclohexylmethyl)ammonio]sulfonate [Streptococcus pneumoniae],4FP3_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(Furan-2-ylmethyl)ammonio]sulfonate [Streptococcus pneumoniae],4FPC_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(4-Chlorobenzyl)ammonio]ethanesulfonate [Streptococcus pneumoniae],4FPE_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(4-Methoxybenzyl)ammonio]ethanesulfonate [Streptococcus pneumoniae],4FPF_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Chlorobenzyl)ammonio]ethanesulfonate [Streptococcus pneumoniae],4FPG_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Hydroxybenzyl)ammonio]ethanesulfonate [Streptococcus pneumoniae],4FPH_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Fluorobenzyl)ammonio]ethanesulfonate [Streptococcus pneumoniae],4FPJ_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Methoxybenzyl)ammonio]ethanesulfonate [Streptococcus pneumoniae],4FPK_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-methylbenzyl)ammonio]ethanesulfonate [Streptococcus pneumoniae],4FPL_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3,4-dichlorobenzyl)ammonio]ethanesulfonate [Streptococcus pneumoniae],4FPO_B Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-chloro-4-methoxybenzyl)ammonio]ethanesulfonate [Streptococcus pneumoniae],4FPY_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Bromobenzyl)ammonio]ethanesulfonate [Streptococcus pneumoniae],4FQ4_A Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(4-Fluoro-3-methylbenzyl)ammonio]ethanesulfonate [Streptococcus pneumoniae] |
4XYX_A | 6.18e-225 | 118 | 773 | 1 | 658 | NanBplus Optactamide [Streptococcus pneumoniae] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
Q54727 | 1.05e-224 | 118 | 773 | 40 | 697 | Sialidase B OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=nanB PE=1 SV=2 |
Q27701 | 2.12e-182 | 120 | 771 | 86 | 755 | Anhydrosialidase OS=Macrobdella decora OX=6405 PE=1 SV=1 |
P29767 | 4.34e-58 | 117 | 745 | 188 | 809 | Sialidase OS=Clostridium septicum OX=1504 PE=3 SV=1 |
P31206 | 2.02e-14 | 323 | 745 | 203 | 526 | Sialidase OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=nanH PE=3 SV=2 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
0.000317 | 0.998723 | 0.000398 | 0.000194 | 0.000184 | 0.000157 |
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