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CAZyme Information: MGYG000003811_01863
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Corynebacterium amycolatum | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Actinobacteriota; Actinomycetia; Mycobacteriales; Mycobacteriaceae; Corynebacterium; Corynebacterium amycolatum | |||||||||||
| CAZyme ID | MGYG000003811_01863 | |||||||||||
| CAZy Family | GT53 | |||||||||||
| CAZyme Description | putative arabinosyltransferase B | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 31; End: 2130 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT53 | 1 | 694 | 1.8e-255 | 0.6282173498570067 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam14896 | Arabino_trans_C | 0.0 | 300 | 694 | 1 | 383 | EmbC C-terminal domain. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol. This domain represents the C-terminal extracellular domain that is likely to bind to carbohydrate. |
| pfam04602 | Arabinose_trans | 6.91e-94 | 2 | 238 | 206 | 437 | Mycobacterial cell wall arabinan synthesis protein. Arabinosyltransferase is involved in arabinogalactan (AG) biosynthesis pathway in mycobacteria. AG is a component of the macromolecular assembly of the mycolyl-AG-peptidoglycan complex of the cell wall. This enzyme has important clinical applications as it is believed to be the target of the antimycobacterial drug Ethambutol. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QPR31462.1 | 0.0 | 2 | 699 | 435 | 1132 |
| QQV00905.1 | 0.0 | 2 | 699 | 435 | 1132 |
| QQB83341.1 | 0.0 | 2 | 699 | 435 | 1132 |
| QQU97311.1 | 0.0 | 2 | 699 | 435 | 1132 |
| ASE57092.1 | 0.0 | 2 | 699 | 435 | 1132 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 7BVE_A | 2.59e-155 | 2 | 694 | 416 | 1071 | Cryo-EMstructure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155],7BVE_B Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155] |
| 7BWR_A | 4.88e-155 | 4 | 697 | 424 | 1081 | Mycobacteriumsmegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound asymmetric 'active state' [Mycolicibacterium smegmatis MC2 155],7BWR_B Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound asymmetric 'active state' [Mycolicibacterium smegmatis MC2 155],7BX8_A Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in symmetric 'resting state' [Mycolicibacterium smegmatis MC2 155],7BX8_B Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in symmetric 'resting state' [Mycolicibacterium smegmatis MC2 155] |
| 7BVH_A | 5.12e-155 | 2 | 694 | 429 | 1084 | Crystalstructure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose [Mycolicibacterium smegmatis MC2 155],7BVH_B Crystal structure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose [Mycolicibacterium smegmatis MC2 155] |
| 6X0O_A | 7.11e-155 | 4 | 697 | 424 | 1081 | Single-ParticleCryo-EM Structure of Arabinosyltransferase EmbB from Mycobacterium smegmatis [Mycolicibacterium smegmatis MC2 155] |
| 7BVC_B | 7.45e-155 | 4 | 697 | 424 | 1081 | Cryo-EMstructure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with ethambutol [Mycolicibacterium smegmatis MC2 155],7BVG_B Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with di-arabinose. [Mycolicibacterium smegmatis MC2 155] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q50395 | 8.93e-156 | 4 | 697 | 424 | 1081 | Probable arabinosyltransferase B OS=Mycolicibacterium smegmatis OX=1772 GN=embB PE=3 SV=3 |
| Q9CDA9 | 1.61e-152 | 4 | 697 | 422 | 1082 | Probable arabinosyltransferase B OS=Mycobacterium leprae (strain TN) OX=272631 GN=embB PE=3 SV=1 |
| Q50393 | 7.12e-152 | 2 | 694 | 416 | 1071 | Probable arabinosyltransferase C OS=Mycolicibacterium smegmatis OX=1772 GN=embC PE=3 SV=2 |
| P71486 | 1.60e-151 | 4 | 697 | 407 | 1064 | Probable arabinosyltransferase B OS=Mycobacterium avium OX=1764 GN=embB PE=3 SV=1 |
| Q9CDA7 | 1.80e-151 | 2 | 694 | 412 | 1068 | Probable arabinosyltransferase C OS=Mycobacterium leprae (strain TN) OX=272631 GN=embC PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000051 | 0.000001 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 15 | 33 |
| 40 | 62 |
| 107 | 129 |
| 136 | 158 |
| 168 | 190 |
| 197 | 219 |
| 239 | 260 |
| 281 | 303 |