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CAZyme Information: MGYG000003815_00838

You are here: Home > Sequence: MGYG000003815_00838

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Succiniclasticum sp900314855
Lineage Bacteria; Firmicutes_C; Negativicutes; Acidaminococcales; Acidaminococcaceae; Succiniclasticum; Succiniclasticum sp900314855
CAZyme ID MGYG000003815_00838
CAZy Family GT9
CAZyme Description ADP-heptose--LPS heptosyltransferase 2
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
359 40895.02 8.3897
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003815 1813778 MAG United States North America
Gene Location Start: 30130;  End: 31209  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000003815_00838.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT9 73 330 4.9e-40 0.9333333333333333

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd03789 GT9_LPS_heptosyltransferase 1.85e-50 5 351 1 275
lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0859 RfaF 1.56e-45 5 354 3 329
ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis].
pfam01075 Glyco_transf_9 2.84e-24 72 322 2 234
Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core.
PRK10916 PRK10916 1.18e-14 5 302 2 292
ADP-heptose--LPS heptosyltransferase RfaF.
PRK10422 PRK10422 5.57e-14 4 297 6 288
lipopolysaccharide core biosynthesis protein; Provisional

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AXB82130.1 3.74e-130 1 354 1 350
AEQ21322.1 8.90e-121 4 354 13 359
AOH48991.1 1.11e-41 11 350 1 331
BBB91611.1 8.55e-40 4 354 10 349
AEQ22076.1 1.11e-33 4 354 7 339

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3TOV_A 6.68e-17 4 306 9 296
Thecrystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008],3TOV_B The crystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008]
1PSW_A 7.59e-12 5 337 2 318
Structureof E. coli ADP-heptose lps heptosyltransferase II [Escherichia coli]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P37421 7.48e-15 5 337 2 318
ADP-heptose--LPS heptosyltransferase 2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rfaF PE=3 SV=1
P37692 4.94e-13 5 337 2 318
ADP-heptose--LPS heptosyltransferase 2 OS=Escherichia coli (strain K12) OX=83333 GN=rfaF PE=1 SV=1
P45042 1.70e-11 5 302 2 292
ADP-heptose--LPS heptosyltransferase 2 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=rfaF PE=3 SV=1
Q57336 5.55e-11 11 302 16 286
Lipopolysaccharide core heptosyltransferase OpsX OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=opsX PE=3 SV=1
P25742 3.27e-09 11 311 1 290
Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli (strain K12) OX=83333 GN=rfaQ PE=3 SV=2

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000061 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003815_00838.