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CAZyme Information: MGYG000003973_01303

You are here: Home > Sequence: MGYG000003973_01303

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species UMGS1312 sp900550625
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; CAG-272; UMGS1312; UMGS1312 sp900550625
CAZyme ID MGYG000003973_01303
CAZy Family GH63
CAZyme Description Periplasmic trehalase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
505 MGYG000003973_23|CGC1 57890.03 4.8573
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003973 2032778 MAG United Kingdom Europe
Gene Location Start: 18466;  End: 19983  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000003973_01303.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH63 87 416 3.2e-34 0.3543859649122807

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3408 GDB1 1.15e-18 93 441 290 620
Glycogen debranching enzyme (alpha-1,6-glucosidase) [Carbohydrate transport and metabolism].
PRK10137 PRK10137 3.42e-17 150 407 417 767
alpha-glucosidase; Provisional
pfam01204 Trehalase 5.49e-11 240 416 317 497
Trehalase. Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a physiological hallmark of heat-shock response in yeast and protects of proteins and membranes against a variety of stresses. This family is found in conjunction with pfam07492 in fungi.
pfam17389 Bac_rhamnosid6H 4.14e-10 145 376 93 289
Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain. This family consists of bacterial rhamnosidase A and B enzymes. L-Rhamnose is abundant in biomass as a common constituent of glycolipids and glycosides, such as plant pigments, pectic polysaccharides, gums or biosurfactants. Some rhamnosides are important bioactive compounds. For example, terpenyl glycosides, the glycosidic precursor of aromatic terpenoids, act as important flavouring substances in grapes. Other rhamnosides act as cytotoxic rhamnosylated terpenoids, as signal substances in plants or play a role in the antigenicity of pathogenic bacteria.
pfam03200 Glyco_hydro_63 8.34e-10 174 418 190 487
Glycosyl hydrolase family 63 C-terminal domain. This is a family of eukaryotic enzymes belonging to glycosyl hydrolase family 63. They catalyze the specific cleavage of the non-reducing terminal glucose residue from Glc(3)Man(9)GlcNAc(2). Mannosyl oligosaccharide glucosidase EC:3.2.1.106 is the first enzyme in the N-linked oligosaccharide processing pathway. This family represents the C-terminal catalytic domain.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QIN83484.1 1.62e-219 20 504 19 511
AIQ57834.1 2.76e-215 12 502 7 497
QHT63246.1 4.07e-209 11 504 29 525
QHT63247.1 9.70e-193 12 502 28 521
BBK93179.1 3.12e-188 11 502 15 505

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3W7S_A 7.57e-13 228 407 551 740
Escherichiacoli K12 YgjK complexed with glucose [Escherichia coli K-12],3W7S_B Escherichia coli K12 YgjK complexed with glucose [Escherichia coli K-12],3W7T_A Escherichia coli K12 YgjK complexed with mannose [Escherichia coli K-12],3W7T_B Escherichia coli K12 YgjK complexed with mannose [Escherichia coli K-12],3W7U_A Escherichia coli K12 YgjK complexed with galactose [Escherichia coli K-12],3W7U_B Escherichia coli K12 YgjK complexed with galactose [Escherichia coli K-12]
3W7X_A 7.57e-13 228 407 551 740
Crystalstructure of E. coli YgjK D324N complexed with melibiose [Escherichia coli K-12],3W7X_B Crystal structure of E. coli YgjK D324N complexed with melibiose [Escherichia coli K-12],5CA3_A Crystal structure of the glycosynthase mutant D324N of Escherichia coli GH63 glycosidase in complex with glucose and lactose [Escherichia coli K-12],5CA3_B Crystal structure of the glycosynthase mutant D324N of Escherichia coli GH63 glycosidase in complex with glucose and lactose [Escherichia coli K-12]
7PQQ_B 8.25e-13 228 407 100 289
ChainB, Anti-RON nanobody,Megabody 91,Glucosidase YgjK [Lama glama]
6XUX_A 8.26e-13 228 407 100 289
ChainA, Nanobody,Glucosidase YgjK,Glucosidase YgjK,Nanobody [Escherichia coli K-12]
7Q6Z_B 8.30e-13 228 407 122 311
ChainB, Megabody 177 [Escherichia coli K-12]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P94250 8.45e-32 96 469 62 431
Uncharacterized protein BB_0381 OS=Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) OX=224326 GN=BB_0381 PE=4 SV=2
P42592 4.21e-12 228 407 574 763
Glucosidase YgjK OS=Escherichia coli (strain K12) OX=83333 GN=ygjK PE=1 SV=1
Q19426 2.36e-08 152 418 490 785
Mannosyl-oligosaccharide glucosidase OS=Caenorhabditis elegans OX=6239 GN=mogs-1 PE=1 SV=2
A7ZZD1 1.29e-06 240 483 340 551
Periplasmic trehalase OS=Escherichia coli O9:H4 (strain HS) OX=331112 GN=treA PE=3 SV=1
P13482 1.29e-06 240 483 340 551
Periplasmic trehalase OS=Escherichia coli (strain K12) OX=83333 GN=treA PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000047 0.000001 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003973_01303.