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CAZyme Information: MGYG000004119_00772

You are here: Home > Sequence: MGYG000004119_00772

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Firmicutes_A; Clostridia; TANB77; CAG-508; CAG-354;
CAZyme ID MGYG000004119_00772
CAZy Family GH23
CAZyme Description Soluble lytic murein transglycosylase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
189 22142.62 8.8761
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004119 1590102 MAG United Kingdom Europe
Gene Location Start: 72182;  End: 72751  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000004119_00772.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH23 53 183 5e-26 0.8296296296296296

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd16896 LT_Slt70-like 1.26e-63 39 182 1 146
uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.
cd13401 Slt70-like 6.71e-56 37 186 1 152
70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda.
cd00254 LT-like 2.75e-38 57 181 1 111
lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.
COG0741 MltE 1.01e-30 38 187 135 287
Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell wall/membrane/envelope biogenesis].
pfam01464 SLT 3.80e-28 48 152 3 106
Transglycosylase SLT domain. This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
SLK19900.1 1.43e-42 25 187 16 179
ATD56881.1 1.43e-42 25 187 16 179
QBJ75740.1 1.43e-42 25 187 16 179
ATD55446.1 1.43e-42 25 187 16 179
ADQ40926.1 1.71e-42 33 187 25 178

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5MPQ_A 2.99e-22 38 187 412 559
BulgecinA: The key to a broad-spectrum inhibitor that targets lytic transglycosylases [Neisseria meningitidis]
5O1J_A 3.01e-22 38 187 416 563
Lytictransglycosylase in action [Neisseria meningitidis MC58]
6FPN_B 3.02e-22 38 187 422 569
Lytictransglycosylase in action [Neisseria meningitidis MC58]
5O24_A 3.04e-22 38 187 426 573
Lytictransglycosylase in action [Neisseria meningitidis]
5O29_A 3.05e-22 38 187 432 579
Lytictransglycosylase in action [Neisseria meningitidis]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
O64046 8.17e-18 38 180 1418 1541
Probable tape measure protein OS=Bacillus phage SPbeta OX=66797 GN=yomI PE=3 SV=1
O31976 8.17e-18 38 180 1418 1541
SPbeta prophage-derived uncharacterized transglycosylase YomI OS=Bacillus subtilis (strain 168) OX=224308 GN=yomI PE=3 SV=2
O31608 8.26e-16 55 180 73 179
Putative murein lytic transglycosylase YjbJ OS=Bacillus subtilis (strain 168) OX=224308 GN=yjbJ PE=3 SV=1
P44888 9.28e-16 34 189 420 577
Putative soluble lytic murein transglycosylase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=slt PE=3 SV=1
P39434 6.91e-14 34 177 472 619
Soluble lytic murein transglycosylase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=slt PE=3 SV=2

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.931936 0.058499 0.004606 0.000359 0.000207 0.004418

TMHMM  Annotations      download full data without filtering help

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