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CAZyme Information: MGYG000004155_00298
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | CAG-273 sp003534295 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; TANB77; CAG-508; CAG-273; CAG-273 sp003534295 | |||||||||||
| CAZyme ID | MGYG000004155_00298 | |||||||||||
| CAZy Family | GH23 | |||||||||||
| CAZyme Description | Soluble lytic murein transglycosylase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 98548; End: 99105 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH23 | 46 | 178 | 4.2e-30 | 0.8296296296296296 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd16896 | LT_Slt70-like | 3.52e-68 | 34 | 178 | 2 | 146 | uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
| cd13401 | Slt70-like | 4.00e-60 | 32 | 182 | 2 | 152 | 70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda. |
| cd00254 | LT-like | 3.20e-41 | 51 | 177 | 1 | 111 | lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
| COG0741 | MltE | 3.60e-35 | 34 | 185 | 137 | 289 | Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell wall/membrane/envelope biogenesis]. |
| pfam01464 | SLT | 7.10e-34 | 42 | 147 | 3 | 105 | Transglycosylase SLT domain. This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AEM78392.1 | 7.81e-45 | 28 | 184 | 27 | 183 |
| AIS52076.1 | 7.81e-45 | 28 | 183 | 27 | 182 |
| ADV80073.1 | 1.11e-44 | 28 | 184 | 27 | 183 |
| ABY95122.1 | 1.72e-44 | 28 | 184 | 42 | 198 |
| ABY93426.1 | 1.72e-44 | 28 | 184 | 42 | 198 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6FBT_A | 2.37e-21 | 54 | 179 | 467 | 592 | ChainA, Lytic murein transglycosylase [Pseudomonas aeruginosa] |
| 5OHU_A | 2.41e-21 | 54 | 179 | 496 | 621 | TheX-ray Structure of Lytic Transglycosylase Slt from Pseudomonas aeruginosa [Pseudomonas aeruginosa] |
| 6FCQ_A | 5.99e-21 | 54 | 179 | 467 | 592 | ChainA, Soluble lytic murein transglycosylase [Pseudomonas aeruginosa],6FCR_A Chain A, Soluble lytic murein transglycosylase [Pseudomonas aeruginosa],6FCS_A Chain A, Soluble lytic murein transglycosylase [Pseudomonas aeruginosa],6FCU_A Chain A, Soluble lytic murein transglycosylase [Pseudomonas aeruginosa] |
| 6FC4_A | 6.00e-21 | 54 | 179 | 468 | 593 | ChainA, Soluble lytic murein transglycosylase [Pseudomonas aeruginosa] |
| 5MPQ_A | 3.25e-17 | 32 | 183 | 412 | 559 | BulgecinA: The key to a broad-spectrum inhibitor that targets lytic transglycosylases [Neisseria meningitidis] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| O31976 | 5.12e-24 | 32 | 176 | 1418 | 1541 | SPbeta prophage-derived uncharacterized transglycosylase YomI OS=Bacillus subtilis (strain 168) OX=224308 GN=yomI PE=3 SV=2 |
| O64046 | 5.12e-24 | 32 | 176 | 1418 | 1541 | Probable tape measure protein OS=Bacillus phage SPbeta OX=66797 GN=yomI PE=3 SV=1 |
| O31608 | 9.72e-22 | 44 | 176 | 68 | 179 | Putative murein lytic transglycosylase YjbJ OS=Bacillus subtilis (strain 168) OX=224308 GN=yjbJ PE=3 SV=1 |
| P44888 | 1.13e-15 | 36 | 182 | 428 | 574 | Putative soluble lytic murein transglycosylase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=slt PE=3 SV=1 |
| P39434 | 1.33e-12 | 36 | 180 | 480 | 626 | Soluble lytic murein transglycosylase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=slt PE=3 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.525299 | 0.461197 | 0.012133 | 0.000375 | 0.000317 | 0.000676 |
