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CAZyme Information: MGYG000004256_01203
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | CAG-177 sp003538135 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; CAG-177; CAG-177 sp003538135 | |||||||||||
| CAZyme ID | MGYG000004256_01203 | |||||||||||
| CAZy Family | GH2 | |||||||||||
| CAZyme Description | Beta-glucuronidase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 99980; End: 101695 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH2 | 14 | 482 | 8.6e-89 | 0.535904255319149 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG3250 | LacZ | 2.03e-39 | 23 | 555 | 15 | 556 | Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]. |
| PRK10150 | PRK10150 | 4.44e-36 | 21 | 440 | 13 | 466 | beta-D-glucuronidase; Provisional |
| PRK10340 | ebgA | 9.06e-15 | 52 | 422 | 99 | 470 | cryptic beta-D-galactosidase subunit alpha; Reviewed |
| pfam02837 | Glyco_hydro_2_N | 1.23e-14 | 23 | 138 | 4 | 131 | Glycosyl hydrolases family 2, sugar binding domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction. |
| pfam02836 | Glyco_hydro_2_C | 5.72e-07 | 274 | 423 | 1 | 157 | Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QHQ60389.1 | 3.84e-262 | 5 | 570 | 4 | 570 |
| ALS26546.1 | 5.10e-245 | 2 | 571 | 6 | 587 |
| QOS82722.1 | 5.12e-243 | 5 | 571 | 4 | 580 |
| QLG42947.1 | 1.41e-242 | 6 | 571 | 5 | 579 |
| AIQ16879.1 | 9.00e-242 | 5 | 571 | 7 | 582 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 7SF2_A | 4.50e-61 | 9 | 551 | 28 | 566 | ChainA, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_B Chain B, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_C Chain C, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_D Chain D, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_E Chain E, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_F Chain F, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838] |
| 6U7I_A | 7.67e-35 | 74 | 419 | 66 | 437 | Faecalibacteriumprausnitzii Beta-glucuronidase [Faecalibacterium prausnitzii],6U7I_B Faecalibacterium prausnitzii Beta-glucuronidase [Faecalibacterium prausnitzii],6U7I_C Faecalibacterium prausnitzii Beta-glucuronidase [Faecalibacterium prausnitzii],6U7I_D Faecalibacterium prausnitzii Beta-glucuronidase [Faecalibacterium prausnitzii] |
| 6U7J_A | 1.13e-33 | 23 | 484 | 24 | 508 | UnculturedClostridium sp. Beta-glucuronidase [uncultured Clostridium sp.],6U7J_B Uncultured Clostridium sp. Beta-glucuronidase [uncultured Clostridium sp.],6U7J_C Uncultured Clostridium sp. Beta-glucuronidase [uncultured Clostridium sp.],6U7J_D Uncultured Clostridium sp. Beta-glucuronidase [uncultured Clostridium sp.] |
| 6LEM_B | 1.05e-31 | 23 | 553 | 13 | 576 | ChainB, Beta-D-glucuronidase [Escherichia coli] |
| 4JKM_A | 1.06e-31 | 16 | 419 | 11 | 438 | CrystalStructure of Clostridium perfringens beta-glucuronidase [Clostridium perfringens str. 13],4JKM_B Crystal Structure of Clostridium perfringens beta-glucuronidase [Clostridium perfringens str. 13],6CXS_A Crystal Structure of Clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine [Clostridium perfringens str. 13],6CXS_B Crystal Structure of Clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine [Clostridium perfringens str. 13] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P05804 | 5.85e-31 | 23 | 553 | 15 | 578 | Beta-glucuronidase OS=Escherichia coli (strain K12) OX=83333 GN=uidA PE=1 SV=2 |
| T2KPJ7 | 3.65e-23 | 75 | 422 | 106 | 464 | Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_21970 PE=2 SV=1 |
| P08236 | 6.10e-21 | 23 | 423 | 41 | 478 | Beta-glucuronidase OS=Homo sapiens OX=9606 GN=GUSB PE=1 SV=2 |
| O77695 | 1.07e-20 | 23 | 423 | 38 | 475 | Beta-glucuronidase (Fragment) OS=Chlorocebus aethiops OX=9534 GN=GUSB PE=2 SV=1 |
| Q5R5N6 | 3.34e-20 | 23 | 423 | 41 | 478 | Beta-glucuronidase OS=Pongo abelii OX=9601 GN=GUSB PE=2 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000041 | 0.000001 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |