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CAZyme Information: MGYG000004266_01588
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Streptococcus sp900550895 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus sp900550895 | |||||||||||
| CAZyme ID | MGYG000004266_01588 | |||||||||||
| CAZy Family | GH73 | |||||||||||
| CAZyme Description | Putative endo-beta-N-acetylglucosaminidase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 346; End: 2415 Strand: + | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG4193 | LytD | 1.56e-46 | 521 | 689 | 58 | 236 | Beta- N-acetylglucosaminidase [Carbohydrate transport and metabolism]. |
| COG5263 | COG5263 | 4.32e-28 | 116 | 412 | 6 | 312 | Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism]. |
| smart00047 | LYZ2 | 1.47e-24 | 565 | 689 | 7 | 147 | Lysozyme subfamily 2. Eubacterial enzymes distantly related to eukaryotic lysozymes. |
| pfam17890 | WW_like | 6.16e-23 | 483 | 535 | 1 | 53 | Peptidoglycan hydrolase LytB WW-like domain. Structural analysis revealed that the catalytic domain of LytB consists of three structurally independent modules: SH3b, WW domain-like, and the glycoside hydrolase family 73 (GH73). This entry is the WW like domain found in endo-beta-N-acetylglucosaminidase LytB from Streptococcus pneumoniae. Functional analysis show that the deletion of both SH3b and WW modules almost completely abolished the activity of LytB. Furthermore, it was shown that the SH3b and WW modules are indispensable for LytB in cell separation. |
| pfam18342 | LytB_WW | 1.19e-22 | 420 | 479 | 4 | 63 | Endo-beta-N-acetylglucosaminidase LytB WW domain. This domain has can be found in endo-beta-N-acetylglucosaminidase LytB (EC 3.2.1.96) of S. pneumoniae and other gram positive bacteria. Comparative analysis revealed that the second all-beta module derived from the WW-like segments is structurally similar to the chitin binding domain of S. marcescens chitinase ChiB, implying a peptide binding function for this module. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QLL98572.1 | 0.0 | 1 | 689 | 1 | 750 |
| CBZ00862.1 | 0.0 | 1 | 689 | 1 | 750 |
| AHZ47906.1 | 0.0 | 1 | 689 | 1 | 750 |
| QXW60772.1 | 0.0 | 1 | 689 | 1 | 750 |
| QLL95967.1 | 0.0 | 1 | 689 | 1 | 750 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 4Q2W_A | 2.67e-119 | 416 | 689 | 16 | 290 | CrystalStructure of pneumococcal peptidoglycan hydrolase LytB [Streptococcus pneumoniae TIGR4] |
| 2WW5_A | 1.06e-18 | 176 | 335 | 44 | 240 | 3D-structureof the modular autolysin LytC from Streptococcus pneumoniae at 1.6 A resolution [Streptococcus pneumoniae R6],2WWD_A 3D-structure of the modular autolysin LytC from Streptococcus pneumoniae in complex with pneummococcal peptidoglycan fragment [Streptococcus pneumoniae R6] |
| 2WWC_A | 1.06e-18 | 176 | 335 | 44 | 240 | 3D-structureof the modular autolysin LytC from Streptococcus pneumoniae in complex with synthetic peptidoglycan ligand [Streptococcus pneumoniae R6] |
| 4PI7_A | 2.75e-17 | 535 | 678 | 52 | 208 | ChainA, Autolysin E [Staphylococcus aureus subsp. aureus Mu50],4PI9_A Chain A, Autolysin E [Staphylococcus aureus subsp. aureus Mu50],4PIA_A Chain A, Autolysin E [Staphylococcus aureus subsp. aureus Mu50] |
| 4PI8_A | 1.70e-16 | 535 | 678 | 52 | 208 | ChainA, Autolysin E [Staphylococcus aureus subsp. aureus Mu50] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P59205 | 3.81e-161 | 176 | 689 | 30 | 658 | Putative endo-beta-N-acetylglucosaminidase OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=lytB PE=1 SV=1 |
| P59206 | 5.75e-154 | 176 | 689 | 30 | 702 | Putative endo-beta-N-acetylglucosaminidase OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) OX=171101 GN=lytB PE=1 SV=1 |
| Q99V41 | 6.21e-13 | 533 | 686 | 1064 | 1236 | Bifunctional autolysin OS=Staphylococcus aureus (strain N315) OX=158879 GN=atl PE=1 SV=1 |
| Q931U5 | 6.21e-13 | 533 | 686 | 1064 | 1236 | Bifunctional autolysin OS=Staphylococcus aureus (strain Mu50 / ATCC 700699) OX=158878 GN=atl PE=1 SV=2 |
| Q6GI31 | 6.22e-13 | 533 | 686 | 1073 | 1245 | Bifunctional autolysin OS=Staphylococcus aureus (strain MRSA252) OX=282458 GN=atl PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000528 | 0.882528 | 0.115977 | 0.000368 | 0.000307 | 0.000260 |