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CAZyme Information: MGYG000004298_00241
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Alphaproteobacteria; RF32; CAG-977; UBA11549; | |||||||||||
| CAZyme ID | MGYG000004298_00241 | |||||||||||
| CAZy Family | GT19 | |||||||||||
| CAZyme Description | Lipid-A-disaccharide synthase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 44490; End: 45665 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT19 | 9 | 364 | 1.6e-118 | 0.9830508474576272 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG0763 | LpxB | 4.98e-132 | 9 | 387 | 4 | 379 | Lipid A disaccharide synthetase [Cell wall/membrane/envelope biogenesis]. |
| PRK00025 | lpxB | 9.16e-132 | 9 | 388 | 4 | 376 | lipid-A-disaccharide synthase; Reviewed |
| pfam02684 | LpxB | 4.51e-96 | 9 | 361 | 1 | 355 | Lipid-A-disaccharide synthetase. This is a family of lipid-A-disaccharide synthetases, EC:2.4.2.128. These enzymes catalyze the reaction: UDP-2,3-bis(3-hydroxytetradecanoyl) glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate <=> UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6 -beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. These enzymes catalyze the fist disaccharide step in the synthesis of lipid-A-disaccharide. |
| TIGR00215 | lpxB | 5.29e-78 | 11 | 357 | 10 | 357 | lipid-A-disaccharide synthase. Lipid-A precursor biosynthesis producing lipid A disaccharide in a condensation reaction. transcribed as part of an operon including lpxA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
| PRK14089 | PRK14089 | 8.52e-49 | 13 | 339 | 8 | 309 | lipid-A-disaccharide synthase. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| BAE51288.1 | 2.33e-133 | 7 | 385 | 1 | 379 |
| ARJ65449.1 | 5.14e-131 | 7 | 385 | 6 | 384 |
| CUW40282.1 | 1.68e-129 | 7 | 385 | 6 | 384 |
| QIM10250.1 | 2.09e-128 | 4 | 386 | 2 | 383 |
| ACI98608.1 | 5.42e-127 | 7 | 386 | 4 | 382 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5W8N_A | 3.76e-62 | 1 | 387 | 1 | 381 | LipidA Disaccharide Synthase (LpxB)-6 solubilizing mutations [Escherichia coli BL21(DE3)] |
| 5W8S_A | 5.29e-62 | 1 | 387 | 1 | 381 | LipidA Disaccharide Synthase (LpxB)-7 solubilizing mutations [Escherichia coli BL21(DE3)],5W8X_A Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations-Bound to UDP [Escherichia coli BL21(DE3)] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q2W4D7 | 4.65e-134 | 7 | 385 | 1 | 379 | Lipid-A-disaccharide synthase OS=Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) OX=342108 GN=lpxB PE=3 SV=1 |
| B6IST7 | 1.08e-127 | 7 | 386 | 4 | 382 | Lipid-A-disaccharide synthase OS=Rhodospirillum centenum (strain ATCC 51521 / SW) OX=414684 GN=lpxB PE=3 SV=1 |
| Q5FUA3 | 8.19e-96 | 9 | 383 | 31 | 402 | Lipid-A-disaccharide synthase OS=Gluconobacter oxydans (strain 621H) OX=290633 GN=lpxB PE=3 SV=1 |
| Q0BS63 | 7.53e-94 | 9 | 388 | 6 | 392 | Lipid-A-disaccharide synthase OS=Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1) OX=391165 GN=lpxB PE=3 SV=1 |
| Q3SRI5 | 8.40e-85 | 9 | 385 | 13 | 387 | Lipid-A-disaccharide synthase OS=Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255) OX=323098 GN=lpxB PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000075 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |