beta-diglucosyldiacylglycerol synthase and similar proteins. beta-diglucosyldiacylglycerol synthase (processive diacylglycerol beta-glucosyltransferase EC 2.4.1.315) is involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. This family of glycosyltransferases also contains plant major galactolipid synthase (chloroplastic monogalactosyldiacylglycerol synthase 1 EC 2.4.1.46). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.

Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only].

putative lipid kinase; Reviewed

putative lipid kinase; Reviewed

monogalactosyldiacylglycerol synthase

CrystalStructure of Diacylglycerol Kinase DgkB in complex with ADP and Mg [Staphylococcus aureus],2QVL_A Crystal Structure of Diacylglycerol Kinase [Staphylococcus aureus]

Thecrystal structure of Arabidopsis thaliana galactolipid synthase, MGD1 (apo-form) [Arabidopsis thaliana],4X1T_A The crystal structure of Arabidopsis thaliana galactolipid synthase MGD1 in complex with UDP [Arabidopsis thaliana]

Structureof an Escherichia coli lipid kinase (YegS) [Escherichia coli BL21(DE3)],2BON_B Structure of an Escherichia coli lipid kinase (YegS) [Escherichia coli BL21(DE3)]

Crystalstructure of YegS in complex with ADP [Escherichia coli BL21]

Crystalstructure of Salmonella typhimurium YegS, a putative lipid kinase homologous to eukaryotic sphingosine and diacylglycerol kinases. [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],2P1R_B Crystal structure of Salmonella typhimurium YegS, a putative lipid kinase homologous to eukaryotic sphingosine and diacylglycerol kinases. [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],2P1R_C Crystal structure of Salmonella typhimurium YegS, a putative lipid kinase homologous to eukaryotic sphingosine and diacylglycerol kinases. [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],2P1R_D Crystal structure of Salmonella typhimurium YegS, a putative lipid kinase homologous to eukaryotic sphingosine and diacylglycerol kinases. [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]

Diacylglycerol kinase OS=Bacillus subtilis (strain 168) OX=224308 GN=dagK PE=1 SV=1

Diacylglycerol kinase OS=Staphylococcus aureus (strain bovine RF122 / ET3-1) OX=273036 GN=dagK PE=3 SV=1

Diacylglycerol kinase OS=Staphylococcus aureus (strain MRSA252) OX=282458 GN=dagK PE=1 SV=1

Diacylglycerol kinase OS=Staphylococcus aureus (strain N315) OX=158879 GN=dagK PE=3 SV=1

Diacylglycerol kinase OS=Staphylococcus aureus (strain JH9) OX=359786 GN=dagK PE=3 SV=1