You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000004535_00528
You are here: Home > Sequence: MGYG000004535_00528
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | UBA10677 sp900767465 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-552; UBA10677; UBA10677 sp900767465 | |||||||||||
| CAZyme ID | MGYG000004535_00528 | |||||||||||
| CAZy Family | GH37 | |||||||||||
| CAZyme Description | Cytoplasmic trehalase | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 18648; End: 20180 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH37 | 237 | 423 | 1.7e-20 | 0.3564154786150713 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| PRK10137 | PRK10137 | 6.66e-14 | 245 | 381 | 597 | 742 | alpha-glucosidase; Provisional |
| pfam03200 | Glyco_hydro_63 | 3.62e-12 | 199 | 425 | 234 | 487 | Glycosyl hydrolase family 63 C-terminal domain. This is a family of eukaryotic enzymes belonging to glycosyl hydrolase family 63. They catalyze the specific cleavage of the non-reducing terminal glucose residue from Glc(3)Man(9)GlcNAc(2). Mannosyl oligosaccharide glucosidase EC:3.2.1.106 is the first enzyme in the N-linked oligosaccharide processing pathway. This family represents the C-terminal catalytic domain. |
| COG3408 | GDB1 | 8.64e-12 | 237 | 475 | 428 | 641 | Glycogen debranching enzyme (alpha-1,6-glucosidase) [Carbohydrate transport and metabolism]. |
| pfam01204 | Trehalase | 1.74e-11 | 241 | 389 | 319 | 466 | Trehalase. Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a physiological hallmark of heat-shock response in yeast and protects of proteins and membranes against a variety of stresses. This family is found in conjunction with pfam07492 in fungi. |
| COG1626 | TreA | 9.63e-11 | 242 | 386 | 370 | 507 | Neutral trehalase [Carbohydrate transport and metabolism]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AVM44762.1 | 7.11e-197 | 1 | 510 | 85 | 596 |
| QZT38129.1 | 1.96e-152 | 15 | 503 | 33 | 496 |
| AOW82330.1 | 4.60e-144 | 6 | 507 | 37 | 512 |
| QWP64175.1 | 4.37e-142 | 10 | 510 | 36 | 508 |
| QWP27558.1 | 4.37e-142 | 10 | 510 | 36 | 508 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3W7S_A | 5.68e-09 | 239 | 381 | 564 | 715 | Escherichiacoli K12 YgjK complexed with glucose [Escherichia coli K-12],3W7S_B Escherichia coli K12 YgjK complexed with glucose [Escherichia coli K-12],3W7T_A Escherichia coli K12 YgjK complexed with mannose [Escherichia coli K-12],3W7T_B Escherichia coli K12 YgjK complexed with mannose [Escherichia coli K-12],3W7U_A Escherichia coli K12 YgjK complexed with galactose [Escherichia coli K-12],3W7U_B Escherichia coli K12 YgjK complexed with galactose [Escherichia coli K-12] |
| 3W7W_A | 5.68e-09 | 239 | 381 | 564 | 715 | Crystalstructure of E. coli YgjK E727A complexed with 2-O-alpha-D-glucopyranosyl-alpha-D-galactopyranose [Escherichia coli K-12],3W7W_B Crystal structure of E. coli YgjK E727A complexed with 2-O-alpha-D-glucopyranosyl-alpha-D-galactopyranose [Escherichia coli K-12],5GW7_A Crystal structure of the glycosynthase mutant E727A of Escherichia coli GH63 glycosidase in complex with glucose and lactose [Escherichia coli K-12],5GW7_B Crystal structure of the glycosynthase mutant E727A of Escherichia coli GH63 glycosidase in complex with glucose and lactose [Escherichia coli K-12] |
| 3W7X_A | 5.68e-09 | 239 | 381 | 564 | 715 | Crystalstructure of E. coli YgjK D324N complexed with melibiose [Escherichia coli K-12],3W7X_B Crystal structure of E. coli YgjK D324N complexed with melibiose [Escherichia coli K-12],5CA3_A Crystal structure of the glycosynthase mutant D324N of Escherichia coli GH63 glycosidase in complex with glucose and lactose [Escherichia coli K-12],5CA3_B Crystal structure of the glycosynthase mutant D324N of Escherichia coli GH63 glycosidase in complex with glucose and lactose [Escherichia coli K-12] |
| 6XUX_A | 6.07e-09 | 239 | 381 | 113 | 264 | ChainA, Nanobody,Glucosidase YgjK,Glucosidase YgjK,Nanobody [Escherichia coli K-12] |
| 7PQQ_B | 6.07e-09 | 239 | 381 | 113 | 264 | ChainB, Anti-RON nanobody,Megabody 91,Glucosidase YgjK [Lama glama] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P94250 | 1.46e-28 | 66 | 453 | 59 | 408 | Uncharacterized protein BB_0381 OS=Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) OX=224326 GN=BB_0381 PE=4 SV=2 |
| P42592 | 3.15e-08 | 239 | 381 | 587 | 738 | Glucosidase YgjK OS=Escherichia coli (strain K12) OX=83333 GN=ygjK PE=1 SV=1 |
| J5K1E2 | 4.06e-08 | 247 | 446 | 514 | 715 | Cytosolic neutral trehalase OS=Beauveria bassiana (strain ARSEF 2860) OX=655819 GN=NTH1 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.999607 | 0.000401 | 0.000010 | 0.000002 | 0.000001 | 0.000003 |