You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000004759_01077
You are here: Home > Sequence: MGYG000004759_01077
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Paraprevotella; | |||||||||||
| CAZyme ID | MGYG000004759_01077 | |||||||||||
| CAZy Family | GH110 | |||||||||||
| CAZyme Description | Alpha-1,3-galactosidase A | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 5797; End: 7485 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH110 | 29 | 544 | 8.8e-184 | 0.9361313868613139 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam13229 | Beta_helix | 6.19e-07 | 418 | 556 | 10 | 125 | Right handed beta helix region. This region contains a parallel beta helix region that shares some similarity with Pectate lyases. |
| cd14251 | PL-6 | 2.31e-05 | 443 | 537 | 266 | 364 | Polysaccharide Lyase Family 6. Polysaccharide Lyase Family 6 is a family of beta-helical polysaccharide lyases. Members include alginate lyase (EC 4.2.2.3) and chondroitinase B (EC 4.2.2.19). Chondroitinase B is an enzyme that only cleaves the beta-(1,4)-linkage of dermatan sulfate (DS), leading to 4,5-unsaturated dermatan sulfate disaccharides as the product. DS is a highly sulfated, unbranched polysaccharide belonging to a family of glycosaminoglycans (GAGs) composed of alternating hexosamine (gluco- or galactosamine) and uronic acid (D-glucuronic or L-iduronic acid) moieties. DS contains alternating 1,4-beta-D-galactosamine (GalNac) and 1,3-alpha-L-iduronic acid units. The related chondroitin sulfate (CS) contains alternating GalNac and 1,3-beta-D-glucuronic acid units. Alginate lyases (known as either mannuronate (EC 4.2.2.3) or guluronate lyases (EC 4.2.2.11) catalyze the degradation of alginate, a copolymer of alpha-L-guluronate and its C5 epimer beta-D-mannuronate. |
| pfam13229 | Beta_helix | 2.77e-05 | 433 | 557 | 2 | 103 | Right handed beta helix region. This region contains a parallel beta helix region that shares some similarity with Pectate lyases. |
| pfam13229 | Beta_helix | 0.003 | 242 | 329 | 69 | 147 | Right handed beta helix region. This region contains a parallel beta helix region that shares some similarity with Pectate lyases. |
| pfam13229 | Beta_helix | 0.003 | 401 | 487 | 50 | 139 | Right handed beta helix region. This region contains a parallel beta helix region that shares some similarity with Pectate lyases. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QUT41083.1 | 1.05e-239 | 18 | 548 | 11 | 541 |
| AAO78266.1 | 1.49e-239 | 18 | 548 | 11 | 541 |
| QMW89154.1 | 1.49e-239 | 18 | 548 | 11 | 541 |
| CAJ33352.1 | 1.49e-239 | 18 | 548 | 11 | 541 |
| QQA10578.1 | 2.35e-238 | 18 | 548 | 11 | 541 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 7JW4_A | 4.47e-50 | 22 | 541 | 25 | 568 | Crystalstructure of PdGH110B in complex with D-galactose [Pseudoalteromonas distincta],7JW4_B Crystal structure of PdGH110B in complex with D-galactose [Pseudoalteromonas distincta] |
| 7JWF_A | 2.20e-49 | 22 | 541 | 25 | 568 | Crystalstructure of PdGH110B D344N in complex with alpha-(1,3)-galactobiose [Pseudoalteromonas distincta],7JWF_B Crystal structure of PdGH110B D344N in complex with alpha-(1,3)-galactobiose [Pseudoalteromonas distincta],7JWF_C Crystal structure of PdGH110B D344N in complex with alpha-(1,3)-galactobiose [Pseudoalteromonas distincta],7JWF_D Crystal structure of PdGH110B D344N in complex with alpha-(1,3)-galactobiose [Pseudoalteromonas distincta] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q8A2Z5 | 2.97e-240 | 18 | 548 | 11 | 541 | Alpha-1,3-galactosidase A OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=glaA PE=3 SV=1 |
| Q64MU6 | 2.26e-121 | 39 | 543 | 45 | 554 | Alpha-1,3-galactosidase A OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=glaA PE=3 SV=1 |
| Q5L7M8 | 8.93e-121 | 39 | 543 | 45 | 554 | Alpha-1,3-galactosidase A OS=Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow) OX=272559 GN=glaA PE=3 SV=1 |
| Q826C5 | 1.68e-97 | 29 | 544 | 50 | 588 | Alpha-1,3-galactosidase A OS=Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680) OX=227882 GN=glaA PE=3 SV=1 |
| B2UL12 | 2.20e-97 | 52 | 541 | 98 | 582 | Alpha-1,3-galactosidase A OS=Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013 / CIP 107961 / Muc) OX=349741 GN=glaA PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.001687 | 0.991816 | 0.005765 | 0.000270 | 0.000221 | 0.000201 |