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CAZyme Information: MGYG000004789_01563
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Streptococcus sp001556435 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus; Streptococcus sp001556435 | |||||||||||
| CAZyme ID | MGYG000004789_01563 | |||||||||||
| CAZy Family | GT1 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 715; End: 1998 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT1 | 15 | 378 | 1.3e-23 | 0.8638743455497382 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd03784 | GT1_Gtf-like | 3.19e-29 | 9 | 384 | 2 | 365 | UDP-glycosyltransferases and similar proteins. This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. |
| COG1819 | YjiC | 8.56e-25 | 9 | 423 | 3 | 399 | UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism]. |
| pfam00201 | UDPGT | 3.51e-04 | 304 | 415 | 315 | 430 | UDP-glucoronosyl and UDP-glucosyl transferase. |
| cd03785 | GT28_MurG | 0.004 | 19 | 134 | 11 | 114 | undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QMI51227.1 | 4.43e-309 | 1 | 427 | 1 | 427 |
| ARC22694.1 | 8.94e-309 | 1 | 427 | 1 | 427 |
| AVH84134.1 | 1.80e-308 | 1 | 427 | 1 | 427 |
| CCB95650.1 | 7.67e-305 | 13 | 427 | 2 | 416 |
| VED67159.1 | 4.81e-265 | 1 | 425 | 1 | 425 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6KQW_A | 1.04e-10 | 10 | 395 | 6 | 356 | ChainA, Uncharacterized UDP-glucosyltransferase YjiC [Bacillus subtilis subsp. subtilis str. 168] |
| 6KQX_A | 1.06e-10 | 10 | 395 | 6 | 356 | ChainA, Uncharacterized UDP-glucosyltransferase YjiC [Bacillus subtilis subsp. subtilis str. 168],7BOV_A Chain A, Uncharacterized UDP-glucosyltransferase YjiC [Bacillus subtilis subsp. subtilis str. 168] |
| 2IYF_A | 2.64e-09 | 1 | 388 | 1 | 358 | Thecrystal structure of macrolide glycosyltransferases: A blueprint for antibiotic engineering [Streptomyces antibioticus],2IYF_B The crystal structure of macrolide glycosyltransferases: A blueprint for antibiotic engineering [Streptomyces antibioticus] |
| 4M83_A | 3.51e-09 | 1 | 388 | 1 | 358 | Ensemblerefinement of protein crystal structure (2IYF) of macrolide glycosyltransferases OleD complexed with UDP and Erythromycin A [Streptomyces antibioticus],4M83_B Ensemble refinement of protein crystal structure (2IYF) of macrolide glycosyltransferases OleD complexed with UDP and Erythromycin A [Streptomyces antibioticus] |
| 4M60_A | 6.24e-09 | 14 | 388 | 17 | 361 | Crystalstructure of macrolide glycosyltransferases OleD [Streptomyces antibioticus],4M7P_A Ensemble refinement of protein crystal structure of macrolide glycosyltransferases OleD [Streptomyces antibioticus] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| O34539 | 5.81e-10 | 10 | 395 | 6 | 356 | NDP-glycosyltransferase YjiC OS=Bacillus subtilis (strain 168) OX=224308 GN=yjiC PE=1 SV=1 |
| E7CQW6 | 9.45e-10 | 14 | 426 | 14 | 438 | UDP-glucosyltransferase A1 OS=Starmerella bombicola OX=75736 GN=ugtA1 PE=1 SV=1 |
| Q53685 | 1.13e-08 | 1 | 388 | 1 | 358 | Oleandomycin glycosyltransferase OS=Streptomyces antibioticus OX=1890 GN=oleD PE=1 SV=1 |
| Q65JC2 | 3.22e-08 | 10 | 395 | 6 | 357 | NDP-glycosyltransferase YjiC OS=Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46) OX=279010 GN=yjiC PE=1 SV=1 |
| Q63ZR6 | 5.47e-08 | 109 | 372 | 135 | 407 | UDP-glucuronosyltransferase 3A1 OS=Xenopus laevis OX=8355 GN=ugt3a1 PE=2 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000030 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |