Species | Megasphaera sp001546855 | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Lineage | Bacteria; Firmicutes_C; Negativicutes; Veillonellales; Megasphaeraceae; Megasphaera; Megasphaera sp001546855 | |||||||||||
CAZyme ID | MGYG000004801_00078 | |||||||||||
CAZy Family | GT83 | |||||||||||
CAZyme Description | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 83763; End: 85373 Strand: - |
Family | Start | End | Evalue | family coverage |
---|---|---|---|---|
GT83 | 3 | 478 | 1.6e-88 | 0.9148148148148149 |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
COG1807 | ArnT | 5.25e-35 | 1 | 408 | 5 | 423 | 4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis]. |
PRK13279 | arnT | 1.03e-19 | 2 | 311 | 6 | 317 | lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase. |
pfam13231 | PMT_2 | 7.30e-10 | 60 | 178 | 1 | 118 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366. |
COG4745 | COG4745 | 2.17e-05 | 46 | 175 | 46 | 177 | Predicted membrane-bound mannosyltransferase [General function prediction only]. |
pfam02366 | PMT | 3.46e-05 | 32 | 177 | 32 | 184 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
ALG41393.1 | 1.59e-281 | 1 | 536 | 1 | 536 |
CCC72525.1 | 1.59e-281 | 1 | 536 | 1 | 536 |
AVO73980.1 | 1.59e-281 | 1 | 536 | 1 | 536 |
AVO26797.1 | 1.85e-280 | 1 | 536 | 1 | 536 |
AXL21032.1 | 6.81e-231 | 1 | 533 | 1 | 535 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
5EZM_A | 3.02e-25 | 30 | 311 | 57 | 348 | CrystalStructure of ArnT from Cupriavidus metallidurans in the apo state [Cupriavidus metallidurans CH34],5F15_A Crystal Structure of ArnT from Cupriavidus metallidurans bound to Undecaprenyl phosphate [Cupriavidus metallidurans CH34] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
A9R091 | 1.80e-26 | 4 | 350 | 9 | 357 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia pestis bv. Antiqua (strain Angola) OX=349746 GN=arnT PE=3 SV=1 |
Q1C744 | 1.80e-26 | 4 | 350 | 9 | 357 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia pestis bv. Antiqua (strain Antiqua) OX=360102 GN=arnT PE=3 SV=1 |
B2K5L1 | 1.80e-26 | 4 | 350 | 9 | 357 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) OX=502801 GN=arnT PE=3 SV=1 |
A7FHH6 | 1.80e-26 | 4 | 350 | 9 | 357 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) OX=349747 GN=arnT PE=3 SV=1 |
B1JJ32 | 1.80e-26 | 4 | 350 | 9 | 357 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) OX=502800 GN=arnT PE=3 SV=1 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
0.322320 | 0.673445 | 0.001389 | 0.000799 | 0.000745 | 0.001283 |
start | end |
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5 | 27 |
54 | 76 |
81 | 103 |
108 | 130 |
137 | 154 |
169 | 191 |
203 | 222 |
256 | 278 |
287 | 304 |
308 | 325 |
338 | 360 |
370 | 389 |
396 | 418 |
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