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CAZyme Information: MGYG000004801_00078

You are here: Home > Sequence: MGYG000004801_00078

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Megasphaera sp001546855
Lineage Bacteria; Firmicutes_C; Negativicutes; Veillonellales; Megasphaeraceae; Megasphaera; Megasphaera sp001546855
CAZyme ID MGYG000004801_00078
CAZy Family GT83
CAZyme Description Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
536 MGYG000004801_2|CGC3 60618.07 9.5058
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004801 2518563 Isolate United States North America
Gene Location Start: 83763;  End: 85373  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000004801_00078.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT83 3 478 1.6e-88 0.9148148148148149

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG1807 ArnT 5.25e-35 1 408 5 423
4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis].
PRK13279 arnT 1.03e-19 2 311 6 317
lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase.
pfam13231 PMT_2 7.30e-10 60 178 1 118
Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.
COG4745 COG4745 2.17e-05 46 175 46 177
Predicted membrane-bound mannosyltransferase [General function prediction only].
pfam02366 PMT 3.46e-05 32 177 32 184
Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ALG41393.1 1.59e-281 1 536 1 536
CCC72525.1 1.59e-281 1 536 1 536
AVO73980.1 1.59e-281 1 536 1 536
AVO26797.1 1.85e-280 1 536 1 536
AXL21032.1 6.81e-231 1 533 1 535

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5EZM_A 3.02e-25 30 311 57 348
CrystalStructure of ArnT from Cupriavidus metallidurans in the apo state [Cupriavidus metallidurans CH34],5F15_A Crystal Structure of ArnT from Cupriavidus metallidurans bound to Undecaprenyl phosphate [Cupriavidus metallidurans CH34]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
A9R091 1.80e-26 4 350 9 357
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia pestis bv. Antiqua (strain Angola) OX=349746 GN=arnT PE=3 SV=1
Q1C744 1.80e-26 4 350 9 357
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia pestis bv. Antiqua (strain Antiqua) OX=360102 GN=arnT PE=3 SV=1
B2K5L1 1.80e-26 4 350 9 357
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) OX=502801 GN=arnT PE=3 SV=1
A7FHH6 1.80e-26 4 350 9 357
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) OX=349747 GN=arnT PE=3 SV=1
B1JJ32 1.80e-26 4 350 9 357
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) OX=502800 GN=arnT PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.322320 0.673445 0.001389 0.000799 0.000745 0.001283

TMHMM  Annotations      download full data without filtering help

start end
5 27
54 76
81 103
108 130
137 154
169 191
203 222
256 278
287 304
308 325
338 360
370 389
396 418